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Why cant you eat grapefruit with some medications?
I occasionaly take 5 mgs of diazapam for anxiety. The bottle says do not eat grapefriut when taking this medication. Why? I dont eat grapefruit but I eat oranges. Is that okay?
Grapefruit and Meds Don't Mix
(The Washington Post, September 26, 2000)
Pity the poor grapefruit. Never as popular as its sweeter sibling the orange, it also possesses a potentially dangerous flaw: When combined with certain medications, the juice of the grapefruit can dramatically boost the amount of a drug in the bloodstream and increase the chance of adverse effects.
Here's why: The intestine is host to an enzyme that, under normal circumstances, breaks drugs down; recommended dosages of drugs take into account this enzyme's effect. But both grapefruit and its juice somehow inhibit the action of this enzyme, and the patient ends up absorbing a much higher dose of the drug than the doctor intended.
Scientists don't know exactly which ingredient in grapefruit is responsible for this perplexing property, but it doesn't appear to be shared by oranges or any other fruit, according to Garvan C. Kane, an internist at the Mayo Clinic who co-authored a comprehensive review paper on grapefruit-drug interactions in the September issue of the Mayo Clinic Proceedings.
What's worrisome is that the drugs that grapefruit interacts with are among today's most commonly prescribed. They include many of the cholesterol-lowering drugs known as statins (such as Zocor and Lipitor), some of the calcium antagonists used to treat high blood pressure (Plendil, Sular), the sedative Valium, the anti-anxiety medication BuSpar and possibly the impotence drug Viagra.
Grapefruit-drug interactions were first noticed about 10 years ago. Although there have been no reports of death or even serious adverse effects associated with the phenomenon, nobody has specifically looked for them. And bad reactions have been reported in people who have combined these drugs with the antibiotic erythromycin, which blocks the same enzyme that grapefruit does.
The effect is akin to an overdose of the drug itself. High doses of statins, for example, can lead to muscle pain or weakness, and in rare instances a condition called rhabdomyolysis, in which excess muscle breakdown can lead to kidney failure. Grapefruit plus calcium antagonists could cause dizziness or faintness. And a higher Valium dose means increased sedation.
Some pharmacies label prescription bottles with a warning not to consume grapefruit juice within two to four hours of taking these medications. But Kane says that might not be a long enough waiting period for the drugs with more serious side effects. "The grapefruit juice effect can last up to 24 hours. Given that most medications are taken on a daily basis, I would advise that a person not take grapefruit juice at all without first discussing it with their doctor," Kane said.
But suppose you wanted to boost the amount of a drug--say, Viagra--in your system. Could you combine it with grapefruit? Not a good idea. Grapefruit might indeed enhance Viagra's potency-inducing property, but at a price: Side effects such as headache, flushing, indigestion and vision changes would likely rise as well.
Kane urges caution. But "I don't want people to panic. With many medications, grapefruit is perfectly safe. It's just a matter of discussing it with your physician."
That view is echoed by Falco Witkamp, director of grapefruit marketing for the Florida Department of Citrus, based in Lakeland, Fla. "There are many foods that interact with medicines, including caffeine and milk. People should always discuss their diet with their doctor," he urged.
And of course grapefruit does have a health upside: Studies have shown that regular consumption reduces the risk for heart disease, stroke and possibly cancer. ###
Scientists discover how Cordyceps mushrooms fight cancer
(NaturalNews) For thousands of years, the mushroom known as Cordyceps has been used in traditional Chinese medicine to treat problems ranging from coughs and fatigue to impotence and cancer. And once Western scientists started considering that anecdotal reports of the mushroom's curative powers might be something more than "folk tales", research started accumulating that backs up many ancient claims about Cordyceps' health benefits. For example, scientists from the University of Nottingham in Great Britain say they've documented how Cordiceps can fight cancer -- and the new discovery could increase the effectiveness of mushroom-derived cancer treatments.For the study, published in the Journal of Biological Chemistry , Dr. Cornelia de Moor of the University of Nottingham and her colleagues investigated a drug called cordycepin, which was originally extracted from wild growing Cordyceps and is now prepared from a cultivated form of the mushroom.
"Because of technical
Online Pharmacy Reviews: Know Your Male Impotence Drug
Generic drugs have the same components as well as reactivity as their original formulation. These are manufactured and sold after the brand-name meds' patent expires. They are just as efficient as their branded counterpart, since they have similar doses, safety, the same use and administration method. Generic drugs are sold in significantly lower prices since competition increases between the original brand name drug and the generic meds.
Men experiencing impotence will not have a problem searching for treatment with generic medication. Impotence takes place if a person is unable to have and/or sustain an erection while engaging in sexual intercourse. Impotence or erectile dysfunction happens even if the person experiences arousal. Common causes are diabetes, neurological problems, cardiovascular diseases and hormonal insufficiencies. This problem can also be caused by psychological difficulties, often corrected by use of placebo treatment. It is noted that estimated 1 out of 10 males are afflicted with recurrent impotence in their lifetime. This problem causes difficulties relating to success and masculinity. Its cultural affiliations cause males to become ashamed and quiet regarding this problem.
...impotence drug - News
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Scientists discover how Cordyceps mushrooms fight cancer For the study, published in the Journal of Biological Chemistry, Dr. Cornelia de Moor of the University of Nottingham and her colleagues investigated a drug and more » |
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Alert issued on anti-impotence drug The Department of Health urges people not to buy or use anti-impotence drug Vegetal Vigra which contains sildenafil and tadalafil which can cause serious and more » |
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Pfizer spent $5.4M lobbying government in 3Q The maker of cholesterol fighter Lipitor, impotence pill Viagra and nerve pain treatment Lyrica spent 75 percent more on lobbying than its $3.1 million and more » |
Urgent Recall Of Huge Quantities Of Herbal Impotence Meds
quantities of powerful erectile dysfunction prescription compounds in particular Sildenafil the active ingredient of the impotence drug Viagra.
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University of Michigan spinoff expected to get $11 million for tumor-fighting ... which carries significant risk of side effects, including incontinence and impotence. Drugs such as Flomax have mixed results, said Davison. and more » |
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